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the origination of living beings-及4何蛍

弌傍�� the origination of living beings 忖方�� 耽匈4000忖

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which forms one of the waste products of animal structures。  And of
late years a number of other compounds�察�such as Butyric Acid�察�and
others�察�have been added to the list。  I need not tell you that
chemistry is an enormous distance from the goal I indicate�察�all I wish
to point out to you is�察�that it is by no means safe to say that that
goal may not be reached one day。  It may be that it is impossible for
us to produce the conditions requisite to the origination of life�察�but
we must speak modestly about the matter�察�and recollect that Science has
put her foot upon the bottom round of the ladder。  Truly he would be a
bold man who would venture to predict where she will be fifty years
hence。

There is another inquiry which bears indirectly upon this question�察�and
upon which I must say a few words。  You are all of you aware of the
phenomena of what is called spontaneous generation。  Our forefathers��
down to the seventeenth century�察�or thereabouts�察�all imagined�察�in
perfectly good faith�察�that certain vegetable and animal forms gave
birth�察�in the process of their decomposition�察�to insect life。  Thus�察�if
you put a piece of meat in the sun�察�and allowed it to putrefy�察�they
conceived that the grubs which soon began to appear were the result of
the action of a power of spontaneous generation which the meat
contained。  And they could give you receipts for making various animal
and vegetable preparations which would produce particular kinds of
animals。  A very distinguished Italian naturalist�察�named Redi�察�took up
the question�察�at a time when everybody believed in it�察�among others our
own great Harvey�察�the discoverer of the circulation of the blood。  You
will constantly find his name quoted�察�however�察�as an opponent of the
doctrine of spontaneous generation�察�but the fact is�察�and you will see it
if you will take the trouble to look into his works�察�Harvey believed it
as profoundly as any man of his time�察�but he happened to enunciate a
very curious propositionthat every living thing came from an 'egg'��
he did not mean to use the word in the sense in which we now employ it��
he only meant to say that every living thing originated in a little
rounded particle of organized substance�察�and it is from this
circumstance�察�probably�察�that the notion of Harvey having opposed the
doctrine originated。  Then came Redi�察�and he proceeded to upset the
doctrine in a very simple manner。  He merely covered the piece of meat
with some very fine gauze�察�and then he exposed it to the same
conditions。  The result of this was that no grubs or insects were
produced�察�he proved that the grubs originated from the insects who came
and deposited their eggs in the meat�察�and that they were hatched by the
heat of the sun。  By this kind of inquiry he thoroughly upset the
doctrine of spontaneous generation�察�for his time at least。

Then came the discovery and application of the microscope to scientific
inquiries�察�which showed to naturalists that besides the organisms which
they already knew as living beings and plants�察�there were an immense
number of minute things which could be obtained apparently almost at
will from decaying vegetable and animal forms。  Thus�察�if you took some
ordinary black pepper or some hay�察�and steeped it in water�察�you would
find in the course of a few days that the water had become impregnated
with an immense number of animalcules swimming about in all
directions。  From facts of this kind naturalists were led to revive the
theory of spontaneous generation。  They were headed here by an English
naturalist��Needham��and afterwards in France by the learned Buffon。
They said that these things were absolutely begotten in the water of
the decaying substances out of which the infusion was made。  It did not
matter whether you took animal or vegetable matter�察�you had only to
steep it in water and expose it�察�and you would soon have plenty of
animalcules。  They made an hypothesis about this which was a very fair
one。  They said�察�this matter of the animal world�察�or of the higher
plants�察�appears to be dead�察�but in reality it has a sort of dim life
about it�察�which�察�if it is placed under fair conditions�察�will cause it
to break up into the forms of these little animalcules�察�and they will
go through their lives in the same way as the animal or plant of which
they once formed a part。

The question now became very hotly debated。  Spallanzani�察�an Italian
naturalist�察�took up opposite views to those of Needham and Buffon�察�and
by means of certain experiments he showed that it was quite possible to
stop the process by boiling the water�察�and closing the vessel in which
it was contained。  ;Oh� ─�said his opponents�察 �but what do you know you
may be doing when you heat the air over the water in this way�拭 �You may
be destroying some property of the air requisite for the spontaneous
generation of the animalcules。;

However�察�Spallanzani's views were supposed to be upon the right side��
and those of the others fell into discredit�察�although the fact was that
Spallanzani had not made good his views。  Well�察�then�察�the subject
continued to be revived from time to time�察�and experiments were made by
several persons�察�but these experiments were not altogether satisfactory。
It was found that if you put an infusion in which animalcules would
appear if it were exposed to the air into a vessel and boiled it�察�and
then sealed up the mouth of the vessel�察�so that no air�察�save such as
had been heated to 212 degrees�察�could reach its contents�察�that then no
animalcules would be found�察�but if you took the same vessel and exposed
the infusion to the air�察�then you would get animalcules。  Furthermore��
it was found that if you connected the mouth of the vessel with a
red´hot tube in such a way that the air would have to pass through the
tube before reaching the infusion�察�that then you would get no
animalcules。  Yet another thing was noticed�此�if you took two flasks
containing the same kind of infusion�察�and left one entirely exposed to
the air�察�and in the mouth of the other placed a ball of cotton wool�察�so
that the air would have to filter itself through it before reaching the
infusion�察�that then�察�although you might have plenty of animalcules in
the first flask�察�you would certainly obtain none from the second。

These experiments�察�you see�察�all tended towards one conclusionthat the
infusoria were developed from little minute spores or eggs which were
constantly floating in the atmosphere�察�which lose their power of
germination if subjected to heat。  But one observer now made another
experiment which seemed to go entirely the other way�察�and puzzled him
altogether。 He took some of this boiled infusion that I have been
speaking of�察�and by the use of a mercurial batha kind of trough used
in laboratorieshe deftly inverted a vessel containing the infusion
into the mercury�察�so that the latter reached a little beyond the level
of the mouth of the 'inverted' vessel。  You see that he thus had a
quantity of the infusion shut off from any possible communication with
the outer air by being inverted upon a bed of mercury。

He then prepared some pure oxygen and nitrogen gases�察�and passed them by
means of a tube going from the outside of the vessel�察�up through the
mercury into the infusion�察�so that he thus had it exposed to a
perfectly pure atmosphere of the same constituents as the external air。
Of course�察�he expected he would get no infusorial animalcules at all in
that infusion�察�but�察�to his great dismay and discomfiture�察�he found he
almost always did get them。

Furthermore�察�it has been found that experiments made in the manner
described above answer well with most infusions�察�but that if you fill
the vessel with boiled milk�察�and then stop the neck with cotton´wool��
you 'will' have infusoria。  So that you see there were two experiments
that brought you to one kind of conclusion�察�and three to another�察�which
was a most unsatisfactory state of things to arrive at in a scientific
inquiry。

Some few years after this�察�the question began to be very hotly discussed
in France。  There was M。 Pouchet�察�a professor at Rouen�察�a very learned
man�察�but certainly not a very rigid experimentalist。  He published a
number of experiments of his own�察�some of which were very ingenious�察�to
show that if you went to work in a proper way�察�there was a truth in the
doctrine of spontaneous generation。  Well�察�it was one of the most
fortunate things in the world that M。  Pouchet took up this question��
because it induced a distinguished French chemist�察�M。 Pasteur�察�to take
up the question on the other side�察�and he has certainly worked it out in
the most perfect manner。  I am glad to say�察�too�察�that he has published
his researches in time to enable me to give you an account of them。  He
verified all the experiments which I have just mentioned to youand
then finding those extraordinary anomalies�察�as in the case of the
mercury bath and the milk�察�he set himself to work to discover their
nature。  In the case of milk he found it to be a question of
temperature。  Milk in a fresh state is slightly alkaline�察�and it is a
very curious circumstance�察�but this very slight degree of alkalinity
seems to have the effect of preserving the organisms which fall into it
from the air from being destroyed at a temperature of 212 degrees��
which is the boiling point。  But if you raise the temperature 10 degrees
when you boil it�察�the milk behaves like everything else�察�and if the air
with which it comes in contact�察�after being boiled at this temperature��
is passed through a red´hot tube�察�you will not get a trace of
organisms。

He then turned his attention to the mercury bath�察�and found on
examination that the surface of the mercury was almost always covered
with a very fine dust。  He found that even the mercury itself was
positively full of organic matters�察�that from being constantly exposed
to the air�察�it had collected an immense number of these infusorial
organisms from the air。  Well�察�under these circumstances he felt that
the case was quite clear�察�and that the mercury was not what it had
appeared to M。 Schwann to be��a bar to the admission of these
organisms�察�but that�察�in reality�察�it acted as a reservoir from which the
infusion was immediately supplied with the 

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