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There¡¡are¡¡several¡¡diseases¡¡of¡¡the¡¡bone¡¡having¡¡direct¡¡bearing¡¡on¡¡the¡¡anomalies¡¡of¡¡the¡¡extremities¡¡which¡¡should¡¡have¡¡mention¡¡here¡£¡¡Osteomalacia¡¡is¡¡a¡¡disease¡¡of¡¡the¡¡bones¡¡in¡¡adult¡¡life£»¡¡occurring¡¡most¡¡frequently¡¡in¡¡puerperal¡¡women£»¡¡but¡¡also¡¡seen¡¡in¡¡women¡¡not¡¡in¡¡the¡¡puerperal¡¡state£»¡¡and¡¡in¡¡men¡£¡¡It¡¡is¡¡characterized¡¡by¡¡a¡¡progressive¡¡softening¡¡of¡¡the¡¡bone¡substance£»¡¡from¡¡a¡¡gradual¡¡absorption¡¡of¡¡the¡¡lime¡¡salts£»¡¡and¡¡gives¡¡rise¡¡to¡¡considerable¡¡deformity£»¡¡and¡¡occasionally¡¡to¡¡spontaneous¡¡fracture¡£
Rachitis¡¡or¡¡rickets¡¡is¡¡not¡¡a¡¡disease¡¡of¡¡adult¡¡life£»¡¡but¡¡of¡¡infancy¡¡and¡¡childhood£»¡¡and¡¡never¡¡occurs¡¡after¡¡the¡¡age¡¡of¡¡puberty¡£¡¡It¡¡seldom¡¡begins¡¡before¡¡six¡¡months¡¡or¡¡after¡¡three¡¡years¡£¡¡There¡¡are¡¡several¡¡theories¡¡as¡¡to¡¡its¡¡causation£»¡¡one¡¡being¡¡that¡¡it¡¡is¡¡due¡¡to¡¡an¡¡abnormal¡¡development¡¡of¡¡acids¡£¡¡There¡¡is¡¡little¡¡doubt¡¡that¡¡defective¡¡nutrition¡¡and¡¡bad¡¡hygienic¡¡surroundings¡¡are¡¡prominent¡¡factors¡¡in¡¡its¡¡production¡£¡¡The¡¡principal¡¡pathologic¡¡change¡¡is¡¡seen¡¡in¡¡the¡¡epiphyseal¡¡lines¡¡of¡¡long¡¡bones¡¡and¡¡beneath¡¡the¡¡periosteum¡£¡¡Figure¡¡213¡¡shows¡¡the¡¡appearance¡¡during¡¡life¡¡of¡¡a