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In¡¡the¡¡same¡¡way¡¡the¡¡laughter¡¡excited¡¡by¡¡jokes¡¡may¡¡be¡¡explained¡£¡¡An¡¡analysis¡¡of¡¡a¡¡joke¡¡shows¡¡that¡¡it¡¡is¡¡composed¡¡of¡¡two¡¡parts¡¡the¡¡first£»¡¡in¡¡which¡¡is¡¡presented¡¡a¡¡subject¡¡that¡¡acts¡¡as¡¡a¡¡stimulus¡¡to¡¡action£»¡¡and¡¡the¡¡second£»¡¡in¡¡which¡¡the¡¡story¡¡turns¡¡suddenly¡¡so¡¡that¡¡the¡¡stimulus¡¡to¡¡action¡¡is¡¡unexpectedly¡¡withdrawn¡£¡¡The¡¡subject¡¡matter¡¡of¡¡the¡¡joke¡¡affects¡¡each¡¡hearer¡¡according¡¡to¡¡the¡¡type¡¡of¡¡stimuli¡¡that¡¡commonly¡¡excites¡¡that¡¡individual¡£¡¡Hence¡¡it¡¡is¡¡that¡¡a¡¡joke¡¡may¡¡convulse¡¡one¡¡person¡¡while¡¡it¡¡bores¡¡another£»¡¡and¡¡so¡¡there¡¡are¡¡jokes¡¡of¡¡the¡¡classes£»¡¡bankers'¡¡jokes£»¡¡politicians'¡¡jokes£»¡¡the¡¡jokes¡¡of¡¡professional¡¡men£»¡¡of¡¡the¡¡plebeian£»¡¡of¡¡the¡¡artist£»¡¡etc¡£¡¡If¡¡the¡¡joke¡¡fails£»¡¡the¡¡integration¡¡products¡¡of¡¡the¡¡excitation¡¡may¡¡be¡¡used¡¡in¡¡physical¡¡resentment¡¡£¨Fig¡£¡¡32£©¡£

Another¡¡type¡¡of¡¡laughter¡¡is¡¡that¡¡associated¡¡with¡¡the¡¡ticklish¡¡points¡¡of¡¡certain¡¡parts¡¡of¡¡the¡¡body£»¡¡the¡¡soles¡¡of¡¡the¡¡feet¡¡and¡¡certain¡¡parts¡¡of¡¡the¡¡trunk¡¡and¡¡of¡¡the¡¡abdomen¡£¡¡¡¡The¡¡excitation¡¡of¡¡the¡¡ticklish¡¡receptors£»¡¡like¡¡pain£»¡¡compels¡¡self¡­defensive¡¡motor¡¡acts¡£¡¡This¡¡response¡¡is¡¡of¡¡phylogenetic¡¡origin£»¡¡and¡¡may¡¡be¡¡awakened¡¡only¡¡by¡¡stimuli¡¡which¡¡are¡¡too¡¡light¡¡to¡¡be¡¡painful¡£¡¡¡¡In¡¡this¡¡connection¡¡it¡¡is¡¡of¡¡interest¡¡to¡¡note¡¡that¡¡a¡¡superficial£»¡¡insect¡­like¡¡contact¡¡with¡¡the¡¡skin¡¡rarely¡¡provokes¡¡laughter£»¡¡and¡¡that¡¡the¡¡tickling¡¡of¡¡the¡¡nasal£»¡¡oral£»¡¡and¡¡pulmonary¡¡tracts¡¡does¡¡not¡¡produce¡¡laughter¡£¡¡The¡¡ticklish¡¡points¡¡that¡¡cause¡¡laughter¡¡are¡¡rather¡¡deeply¡¡placed£»¡¡and¡¡a¡¡certain¡¡type¡¡of¡¡physical¡¡contact¡¡is¡¡required¡¡to¡¡constitute¡¡an¡¡adequate¡¡stimulus¡£¡¡¡¡That¡¡is£»¡¡the¡¡contact¡¡must¡¡arouse¡¡a¡¡phylogenetic¡¡association¡¡with¡¡a¡¡physical¡¡struggle¡¡or¡¡with¡¡physical¡¡exertion¡£¡¡In¡¡the¡¡foot£»¡¡the¡¡adequate¡¡stimuli¡¡for¡¡laughter¡¡are¡¡such¡¡contacts¡¡as¡¡resemble¡¡or¡¡suggest¡¡piercing¡¡by¡¡stones¡¡or¡¡rough¡¡objects¡£¡£¡¡The¡¡intention¡¡of¡¡the¡¡one¡¡who¡¡tickles¡¡must¡¡be¡¡known£»¡¡if¡¡his¡¡intention¡¡be¡¡playful£»¡¡laughter¡¡results£»¡¡whereas¡¡if¡¡injury¡¡be¡¡intended£»¡¡then¡¡an¡¡effort¡¡toward¡¡escape¡¡or¡¡defense¡¡is¡¡excited£»¡¡but¡¡no¡¡laughter¡£¡¡If¡¡deep¡¡tickling¡¡of¡¡the¡¡ribs¡¡is¡¡known¡¡to¡¡be¡¡malicious£»¡¡it¡¡will¡¡excite¡¡physical¡¡resentment¡¡and¡¡not¡¡laughter¡£¡¡¡¡Self¡­tickling¡¡rarely¡¡causes¡¡laughter¡¡for¡¡the¡¡reason¡¡that¡¡auto¡­tickling¡¡can¡¡cause¡¡only¡¡a¡¡known¡¡degree¡¡of¡¡stimulation£»¡¡so¡¡that¡¡there¡¡results¡¡no¡¡excessive¡¡integration¡¡which¡¡requires¡¡relief¡¡by¡¡the¡¡neutral¡¡muscular¡¡activity¡¡of¡¡laughter¡£¡¡In¡¡fact£»¡¡one¡¡never¡¡sees¡¡purposeful¡¡acts¡¡and¡¡laughter¡¡associated¡£¡¡According¡¡to¡¡its¡¡severity£»¡¡an¡¡isolated¡¡stimulus¡¡causes¡¡either¡¡an¡¡action¡¡or¡¡laughter¡£¡¡¡¡The¡¡ticklish¡¡points¡¡in¡¡our¡¡bodies¡¡were¡¡probably¡¡developed¡¡as¡¡a¡¡means¡¡of¡¡defense¡¡against¡¡serious¡¡attacks¡¡and¡¡of¡¡escape¡¡from¡¡injurious¡¡contacts¡£

Anger£»¡¡fear£»¡¡and¡¡grief¡¡are¡¡also¡¡strong¡¡excitants¡¡and£»¡¡therefore£»¡¡are¡¡stimuli¡¡to¡¡motor¡¡activity¡£¡¡¡¡It¡¡is¡¡obvious¡¡that¡¡whatever¡¡the¡¡excitant¡¡the¡¡physico¡­chemical¡¡action¡¡of¡¡the¡¡brain¡¡and¡¡the¡¡ductless¡¡glands¡¡cannot¡¡be¡¡reversedthe¡¡effect¡¡of¡¡the¡¡stimulus¡¡cannot¡¡be¡¡recalled£»¡¡therefore¡¡either¡¡a¡¡purposeful¡¡muscular¡¡act¡¡or¡¡a¡¡neutralizing¡¡act¡¡must¡¡be¡¡performed¡¡or¡¡else¡¡the¡¡liberated¡¡energy¡¡must¡¡smoulder¡¡in¡¡the¡¡various¡¡parts¡¡of¡¡the¡¡body¡£

It¡¡is¡¡on¡¡this¡¡hypothesis¡¡that¡¡the¡¡origin¡¡and¡¡the¡¡purpose¡¡of¡¡laughter¡¡and¡¡crying¡¡may¡¡be¡¡understood¡£¡¡¡¡Even¡¡a¡¡superficial¡¡analysis¡¡of¡¡the¡¡phenomena¡¡of¡¡both¡¡laughter¡¡and¡¡crying¡¡show¡¡them¡¡to¡¡be¡¡without¡¡any¡¡external¡¡motor¡¡purpose£»¡¡the¡¡respiratory¡¡mechanism¡¡is¡¡intermittently¡¡stimulated¡¡and¡¡inhibited£»¡¡and¡¡the¡¡shoulder¡¡and¡¡arm¡¡muscles£»¡¡indeed£»¡¡many¡¡muscles¡¡of¡¡the¡¡trunk¡¡and¡¡the¡¡extremities¡¡are£»¡¡as¡¡far¡¡as¡¡any¡¡external¡¡design¡¡is¡¡concerned£»¡¡purposelessly¡¡contracted¡¡and¡¡released¡¡until¡¡the¡¡kinetic¡¡energy¡¡mobilized¡¡by¡¡excitation¡¡is¡¡utilized¡£¡¡During¡¡this¡¡time¡¡the¡¡facial¡¡expression¡¡gives¡¡the¡¡index¡¡to¡¡the¡¡mental¡¡state¡£

Crying£»¡¡like¡¡laughter£»¡¡is¡¡always¡¡preceded¡¡by¡¡a¡¡stimulation¡¡to¡¡some¡¡motor¡¡action¡¡which¡¡may¡¡or¡¡may¡¡not¡¡be¡¡performed¡¡£¨Figs¡£¡¡33¡¡and¡¡34£©¡£¡¡If¡¡a¡¡mother¡¡is¡¡anxiously¡¡watching¡¡the¡¡course¡¡of¡¡a¡¡serious¡¡illness¡¡of¡¡her¡¡child¡¡and¡¡if£»¡¡in¡¡caring¡¡for¡¡it£»¡¡she¡¡is¡¡stimulated¡¡to¡¡the¡¡utmost¡¡to¡¡perform¡¡motor¡¡acts£»¡¡she¡¡will¡¡continue¡¡in¡¡a¡¡state¡¡of¡¡motor¡¡tenseness¡¡until¡¡the¡¡child¡¡recovers¡¡or¡¡dies¡£¡¡If¡¡relief¡¡is¡¡sudden£»¡¡as¡¡in¡¡the¡¡crisis¡¡of¡¡pneumonia£»¡¡and¡¡the¡¡mother¡¡is¡¡not¡¡exhausted£»¡¡she¡¡will¡¡easily¡¡laugh¡¡if¡¡tired£»¡¡she¡¡may¡¡cry¡£¡¡If¡¡death¡¡occurs£»¡¡the¡¡stimulus¡¡to¡¡motor¡¡acts¡¡is¡¡suddenly¡¡withdrawn¡¡and¡¡she¡¡then¡¡cries¡¡aloud£»¡¡and¡¡performs¡¡many¡¡motor¡¡acts¡¡as¡¡a¡¡result¡¡of¡¡the¡¡intense¡¡stimulation¡¡to¡¡motor¡¡activity¡¡which¡¡is¡¡no¡¡longer¡¡needed¡¡in¡¡the¡¡physical¡¡care¡¡of¡¡her¡¡child¡£¡¡With¡¡this¡¡clue¡¡we¡¡can¡¡find¡¡the¡¡explanation¡¡of¡¡many¡¡phenomena¡£¡¡¡¡We¡¡can¡¡understand¡¡why¡¡laughter¡¡and¡¡crying¡¡are¡¡so¡¡frequently¡¡interchangeable£»¡¡why¡¡they¡¡often¡¡blend¡¡and¡¡why¡¡either¡¡gives¡¡a¡¡sense¡¡of¡¡relief£»¡¡we¡¡can¡¡understand¡¡why¡¡either¡¡laughter¡¡or¡¡crying¡¡can¡¡come¡¡only¡¡when¡¡the¡¡issue¡¡that¡¡causes¡¡the¡¡integration¡¡is¡¡determined£»¡¡we¡¡can¡¡understand¡¡the¡¡extraordinary¡¡tendency¡¡to¡¡laughter¡¡that¡¡discloses¡¡the¡¡unspoken¡¡sentiments¡¡of¡¡love£»¡¡we¡¡can¡¡understand¡¡the¡¡tears¡¡of¡¡the¡¡woman¡¡when¡¡she¡¡receives¡¡a¡¡proposal¡¡of¡¡marriage¡¡from¡¡the¡¡man¡¡she¡¡loves£»¡¡we¡¡can¡¡understand¡¡why¡¡any¡¡averted¡¡circumstance£»¡¡such¡¡as¡¡a¡¡threatened¡¡breach¡¡of¡¡the¡¡conventions£»¡¡which¡¡would¡¡have¡¡led¡¡to¡¡embarrassment¡¡or¡¡humiliation£»¡¡leads¡¡to¡¡a¡¡tendency¡¡to¡¡laughter£»¡¡and¡¡why¡¡the¡¡recital¡¡of¡¡heroic¡¡deeds¡¡by¡¡association¡¡leads¡¡to¡¡tears£»¡¡On¡¡the¡¡other¡¡hand£»¡¡under¡¡the¡¡domination¡¡of¡¡acute¡¡diseases£»¡¡of¡¡acute¡¡fear£»¡¡or¡¡of¡¡great¡¡exhaustion£»¡¡there¡¡is¡¡usually¡¡neither¡¡laughter¡¡nor¡¡crying¡¡because¡¡the¡¡nervous¡¡system¡¡is¡¡under¡¡the¡¡control¡¡of¡¡a¡¡dominating¡¡influence¡¡as¡¡a¡¡result¡¡of¡¡which¡¡the¡¡body¡¡is¡¡so¡¡exhausted¡¡that¡¡the¡¡excess¡¡of¡¡energy¡¡which¡¡alone¡¡can¡¡produce¡¡laughing¡¡or¡¡crying¡¡is¡¡lacking¡£

A¡¡remarkable¡¡study¡¡of¡¡the¡¡modification¡¡of¡¡laughter¡¡and¡¡crying¡¡by¡¡disease¡¡is¡¡found¡¡in¡¡that¡¡most¡¡interesting¡¡of¡¡diseasesexophthalmic¡¡goiter¡£¡¡In¡¡this¡¡disease¡¡there¡¡is¡¡a¡¡low¡¡threshold¡¡to¡¡all¡¡stimuli¡£¡¡That¡¡the¡¡very¡¡motor¡¡mechanism¡¡of¡¡which¡¡we¡¡have¡¡been¡¡speaking¡¡is¡¡involved£»¡¡is¡¡shown¡¡by¡¡an¡¡enormous¡¡increase¡¡in¡¡its¡¡activity¡£¡¡There¡¡is¡¡also¡¡an¡¡increase¡¡in¡¡the¡¡size¡¡of¡¡certain¡¡at¡¡least¡¡of¡¡the¡¡activating¡¡glandsthe¡¡thyroid¡¡and¡¡the¡¡adrenals¡¡are¡¡enlarged¡¡and¡¡overactive¡¡and¡¡the¡¡glycogen¡­producing¡¡function¡¡of¡¡the¡¡liver¡¡is¡¡stimulated¡£¡¡The¡¡most¡¡striking¡¡phenomenon¡¡of¡¡this¡¡disease£»¡¡however£»¡¡is¡¡the¡¡remarkable¡¡lowering¡¡of¡¡the¡¡brain¡¡thresholds¡¡to¡¡stimuli¡£¡¡¡¡In¡¡other¡¡words£»¡¡in¡¡Graves'¡¡disease¡¡the¡¡nervous¡¡system¡¡and¡¡the¡¡activating¡¡glands¡¡the¡¡entire¡¡motor¡¡mechanismare¡¡in¡¡an¡¡exalted¡¡state¡¡of¡¡activity¡£

If¡¡this¡¡be¡¡true£»¡¡then¡¡these¡¡patients¡¡should¡¡exhibit¡¡behavior¡¡precisely¡¡contrary¡¡to¡¡that¡¡of¡¡those¡¡suffering¡¡from¡¡acute¡¡infection£»¡¡that¡¡is£»¡¡they¡¡should¡¡be¡¡constantly¡¡clearing¡¡their¡¡systems¡¡of¡¡these¡¡superabundant¡¡energizing¡¡materials¡¡by¡¡crying¡¡or¡¡laughing£»¡¡and¡¡this¡¡is¡¡precisely¡¡what¡¡happensthe¡¡flood¡­gates¡¡of¡¡tears¡¡are¡¡open¡¡much¡¡of¡¡the¡¡time¡¡in¡¡Graves'¡¡diseasea¡¡disease¡¡of¡¡the¡¡emotions¡£

We¡¡have¡¡already¡¡interpreted¡¡pain¡¡as¡¡a¡¡phenomenon¡¡of¡¡motor¡¡activity¡£¡¡When¡¡pain¡¡does¡¡not¡¡lead¡¡to¡¡muscular¡¡activity¡¡it¡¡therefore¡¡frequently¡¡leads¡¡to¡¡crying¡¡or¡¡to¡¡moaning£»¡¡just¡¡as¡¡tickling£»¡¡which¡¡is¡¡equally¡¡an¡¡incentive¡¡to¡¡motor¡¡activity£»¡¡results¡¡in¡¡laughter¡¡if¡¡it¡¡does¡¡not¡¡find¡¡full¡¡expression¡¡in¡¡action¡£

From¡¡the¡¡foregoing¡¡we¡¡infer¡¡that¡¡pain£»¡¡the¡¡intense¡¡motor¡¡response¡¡to¡¡tickling£»¡¡and¡¡emotional¡¡excitation¡¡are¡¡all¡¡primitive¡¡biologic¡¡reactions¡¡for¡¡the¡¡good¡¡of¡¡the¡¡individual£»¡¡and¡¡that¡¡all¡¡have¡¡their¡¡origin¡¡in¡¡the¡¡operation¡¡of¡¡the¡¡great¡¡laws¡¡of¡¡evolution¡£¡¡If¡¡to¡¡this¡¡inference¡¡we¡¡add¡¡the¡¡physiologic¡¡dictum¡¡that¡¡the¡¡nervous¡¡system¡¡always¡¡acts¡¡as¡¡a¡¡whole£»¡¡and¡¡that¡¡it¡¡can¡¡respond¡¡to¡¡but¡¡one¡¡stimulus¡¡at¡¡a¡¡time£»¡¡we¡¡can¡¡easily¡¡understand¡¡that¡¡while¡¡diverse¡¡causes¡¡may¡¡integrate¡¡the¡¡nervous¡¡system¡¡for¡¡a¡¡specific¡¡action£»¡¡if¡¡the¡¡cause¡¡be¡¡suddenly¡¡removed£»¡¡then¡¡the¡¡result¡¡of¡¡the¡¡integration¡¡of¡¡the¡¡nervous¡¡system¡¡may¡¡be£»¡¡not¡¡a¡¡specific¡¡action£»¡¡but¡¡an¡¡undesigned¡¡muscular¡¡action£»¡¡such¡¡as¡¡crying¡¡or¡¡laughter¡£¡¡Hence¡¡it¡¡is¡¡that¡¡laughter¡¡and¡¡crying¡¡may¡¡be¡¡evoked¡¡by¡¡diverse¡¡exciting¡¡causes¡£¡¡¡¡The¡¡intensity¡¡of¡¡the¡¡laughter¡¡or¡¡of¡¡the¡¡crying¡¡depends¡¡upon¡¡the¡¡intensity¡¡of¡¡the¡¡stimulus¡¡and¡¡the¡¡dynamic¡¡state¡¡of¡¡the¡¡individual¡£

The¡¡linking¡¡together¡¡of¡¡these¡¡apparently¡¡widely¡¡separated¡¡phenomena¡¡by¡¡the¡¡simple¡¡law¡¡of¡¡the¡¡discharge¡¡of¡¡energy¡¡by¡¡association¡¡perhaps¡¡explains¡¡the¡¡association¡¡of¡¡an¡¡abnormal¡¡tendency¡¡to¡¡tears¡¡with¡¡an¡¡abnormally¡¡low¡¡threshold¡¡for¡¡pain¡¡£¨Fig¡£¡¡36£©¡£¡¡In¡¡the¡¡neurasthenic£»¡¡tears¡¡and¡¡pain¡¡are¡¡produced¡¡with¡¡abnormal¡¡facility¡£¡¡¡¡Hence¡¡it¡¡is¡¡that£»¡¡if¡¡a¡¡patient¡¡about¡¡to¡¡undergo¡¡a¡¡surgical¡¡operation¡¡is¡¡in¡¡a¡¡state¡¡of¡¡fear¡¡and¡¡dread¡¡before¡¡the¡¡operation£»¡¡the¡¡threshold¡¡to¡¡all¡¡stimuli¡¡is¡¡lowered£»¡¡and¡¡this¡¡lowered¡¡threshold¡¡will¡¡continue¡¡throughout¡¡the¡¡operation£»¡¡even¡¡under¡¡inhalation¡¡anesthesia£»¡¡because¡¡the¡¡stimulus¡¡produced¡¡by¡¡cutting¡¡sensitive¡¡tissue¡¡is¡¡transmitted¡¡to¡¡the¡¡brain¡¡just¡¡as¡¡readily¡¡as¡¡if¡¡the¡¡patient¡¡were¡¡not¡¡anesthetized¡£¡¡¡¡In¡¡like¡¡manner£»¡¡the¡¡brain¡¡may¡¡be¡¡sensitized¡¡by¡¡the¡¡administration¡¡of¡¡large¡¡doses¡¡of¡¡thyroid¡¡extract¡¡prior¡¡to¡¡operation£»¡¡the¡¡threshold¡¡to¡¡injury¡¡in¡¡such¡¡a¡¡case¡¡continuing¡¡to¡¡be¡¡low¡¡to¡¡traumatic¡¡stimuli¡¡even¡¡under¡¡anesthesia¡£¡¡Under¡¡the¡¡sensitizing¡¡influences¡¡of¡¡thyroid¡¡extract¡¡or¡¡of¡¡Graves'¡¡disease¡¡the¡¡effect¡¡of¡¡an¡¡injury£»¡¡of¡¡an¡¡operation£»¡¡or¡¡of¡¡emotional¡¡excitation¡¡is¡¡heightened¡£¡¡¡¡The¡¡extent¡¡to¡¡which¡¡the¡¡threshold¡¡to¡¡pain¡¡or¡¡to¡¡any¡¡other¡¡excitant¡¡is¡¡affected¡¡by¡¡Graves'¡¡disease¡¡is¡¡illustrated¡¡by¡¡the¡¡almost¡¡fatal¡¡reaction¡¡which¡¡I¡¡once¡¡saw¡¡result¡¡from¡¡the¡¡mere¡¡pricking¡¡with¡¡a¡¡hypodermic¡¡needle¡¡of¡¡a¡¡patient¡¡with¡¡this¡¡disease¡£¡¡As¡¡the¡¡result¡¡of¡¡a¡¡visit¡¡from¡¡a¡¡friend£»¡¡the¡¡pulse¡­rate¡¡of¡¡a¡¡victim¡¡of¡¡this¡¡disease¡¡may¡¡increase¡¡twenty¡¡beats¡¡and¡¡his¡¡temperature¡¡rise¡¡markedly¡£¡¡I¡¡have¡¡seen¡¡the¡¡mere¡¡suggestion¡¡of¡¡an¡¡operation¡¡produce¡¡collapse¡£¡¡As¡¡the¡¡brain¡¡is¡¡thus¡¡remarkably¡¡sensitized¡¡in¡¡Graves'¡¡disease£»¡¡we¡¡find¡¡that¡¡in¡¡these¡¡patients¡¡laughter£»¡¡crying£»¡¡emotional¡¡disturbances£»¡¡and¡¡surgical¡¡shock¡¡are¡¡produced¡¡with¡¡remarkable¡¡facility¡£

I¡¡hope¡¡that¡¡even¡¡this¡¡admittedly¡¡crude¡¡and¡¡imperfect¡¡consideration¡¡of¡¡this¡¡subject¡¡will¡¡suggest¡¡the¡¡possibility¡¡of¡¡establishing¡¡a¡¡practical¡¡viewpoint¡¡as¡¡to¡¡the¡¡origin¡¡and¡¡purpose¡¡of¡¡pain£»¡¡of¡¡tickling£»¡¡and¡¡of¡¡such¡¡expressions¡¡of¡¡emotion¡¡as¡¡laughter¡¡and¡¡crying£»¡¡and¡¡that¡¡it¡¡may¡¡help¡¡us¡¡to¡¡understand¡¡their¡¡significance¡¡in¡¡health¡¡and¡¡in¡¡disease¡£



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